Micky van de Ven Brace Ends The Toffees' Run at Brand New Stadium
The Dutch defender became the initial defender to net two goals in a Premier League match for Spurs since Jan Vertonghen in March 2013.
At a glance
The Spurs defender nods home twice in opening period
Everton's Jake O'Brien has goal ruled after video check
Senegalese midfielder scores third in dying moments
This loss is the Merseyside club's initial at their new ground
Micky van de Ven found the net on two occasions as Spurs extended their winning streak on the road in the top division and delivered Everton their first defeat at their new home.
Everton were unbeaten in their last five matches at their new ground at Bramley-Moore Dock, having left their historic home behind after 133 years at the conclusion of last season.
But Spurs captain the Dutchman pounced twice from corners in the first half to put their impressive record at risk, and they were failed to mount a comeback before the midfielder - set up by ex-Everton forward the Brazilian - nodded in a final goal to seal the victory.
The Everton defender believed he had equalized the tally a short while after the defender's opener, glancing a bullet header past Guglielmo Vicario from an Everton corner.
The Portuguese striker, meanwhile, missed a handful of opportunities, while Vicario made a series of excellent saves to guarantee Tottenham went five away games without defeat in the Premier League.
But the VAR stepped in, advising the match official to review the goal on the pitchside monitor and the referee ruled that Jack Grealish and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.
The win elevates Thomas Frank's side into third place in the division, five points off north London rivals and table-toppers the Gunners.
The Merseyside club remain 14th and are half a dozen points clear of the drop zone.
Spurs breakdown: The defender fulfils role at each end of the field
Following a drab midweek performance in the Champions League against the French side, where they mustered a only two shots on target, the manager chose the French striker up front instead of former Toffees player the Brazilian.
The summer signing was failed to influence the game before being replaced for the substitute after an hour on the field, but it turns out he wasn't needed in the final outcome.
Centre-back the Dutchman transformed into an attacking force to be feared.
Tottenham's opening strike came from a cleverly executed set-piece play, with Rodrigo Bentancur heading the ball toward the six-yard box for an unmarked Van de Ven to head home.
And Ven de Ven - stepping up as captain in Cristian Romero's unavailability - added his next goal in added time as he outjumped Jordan Pickford to nod in.
The Dutchman was equally outstanding in defensive duties, partnering effectively with Kevin Danso as the pair handled superbly with the numerous deliveries sent their way by the opposition.
Toffees breakdown: Everton missing finishing touch
The club's new home had been a happy hunting ground, but it seems the freshness may have worn off somewhat and supporters flocked to the gates after the midfielder's final goal for Spurs.
The end in Everton's winning streak at home will not be a massive worry for David Moyes, but their attacking woes will be.
The forward and the other striker - the Everton's two established centre-forwards - had netted just a single goal combined before Sunday's outing.
And they were unable to contribute to that miserable record on a damp and dreary night on in Liverpool.
Beto's performance was epitomized when he opted to bicycle-kick a golden opportunity from close range, even with having space and time to reposition for a simpler attempt that would have challenged the keeper.
Barry, too, was unable to influence the game after replacing the starter in the 65th minute.
It was not for a shortage of opportunity. The majority of the home side's attacks came through Grealish and Ndiaye, who tirelessly delivered dangerous crosses into the Spurs penalty area.
What next for these two sides?
Everton: Moyes' men travel to Sunderland in the top flight on early November at 8 PM.
Tottenham: The London club go to Newcastle's ground on Wednesday, 29 October for their next round Carabao Cup tie against Newcastle.